Mutation of the KIT (mast/stem cell growth factor receptor) protooncogene in human piebaldism.
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منابع مشابه
Mutation of the KIT (mast/stem cell growth factor receptor) protooncogene in human piebaldism.
Piebaldism is an autosomal dominant genetic disorder characterized by cogenital patches of skin and hair from which melanocytes are completely absent. A similar disorder of mouse, dominant white spotting (W), results from mutations of the c-Kit protooncogene, which encodes and receptor for mast/stem cell growth factor. We identified a KIT gene mutation in a proband with classic autosomal domina...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1991
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.88.19.8696